The Magic Ball of Biology - Magnetic Beads SPRI (Solid Phase Reverse Immobilization) is that paramagnetic beads can selectively bind to nucleic acids by type and size, and can be used to isolate, purify and clean up high purity nucleic acids. This technology can be applied to next generation sequencing (NGS), Sanger sequencing, qPCR, ddPCR and microarrays, etc.